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A new study of why older male flies are more likely to pass mutations onto their offspring may shine a light on inherited diseases.

Researchers from Rockefeller University found that the repair mechanisms through which mutations are removed during the production of sperm did not occur within the testes of older individuals.

A new study describes why older male fruit flies are more likely to pass on mutations, potentially shining a light on inherited-disease risk in humans.

Washington, Jan 14: Scientists have described why older male fruit flies are more likely to pass mutations onto their offspring in a new study, potentially shedding light on the risk of inherited-disease in humans. The male reproductive system serves as a hotspot for the emergence of new genes. Perhaps that explains why more new mutations are inherited from fathers than from mothers. This does not, however, clarify why older fathers pass on more mutations than younger ones do. The mechanisms […]