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Researchers discover gene that impacts the development of Ewing sarcoma in children Researchers have discovered a gene, OTUD7A, that impacts the development of Ewing sarcoma, a bone cancer that occurs mainly in children. They have also identified a compound that shows potential to block OTUD7A protein activity. The finding, by scientists at the University of North Carolina and the Lineberger Comprehensive Cancer Center, appeared online June 1, 2021, in Advanced Science. About 250 children and young adults are diagnosed with Ewing sarcoma each year in the U.S. About half of those diagnosed wi...

"What we found was that Ewing sarcoma cells are able to develop an antioxidant response that shields them and allows them to survive as they circulate. This is similar to a person in the Arctic having to put a thick coat on before they go outside. If they don't shield themselves, they are exposed to dangerously harsh conditions that they may not survive under," said senior author Dr. Poul Sorensen, a scientist at BC Cancer and professor of pathology and laboratory medicine at the University of British Columbia. "What's exciting about this study is if we can target the cells in circulation the...

A new discovery in Ewing sarcoma, an aggressive and often fatal childhood cancer, has uncovered the potential to prevent cancer cells from spreading beyond their primary tumor site.

Is it 'just' a hematoma or something more sinister?

For 10 months, Noah Adams fought Ewing sarcoma, an aggressive type of bone cancer. He got...