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Long telomere syndrome is associated with an increased risk of developing neoplasms

1. In this case series, protection of telomeres 1 (POT1) mutations associated with long telomere length conferred an increased risk of developing benign and malignant solid neoplasms. 2. The risk of developing these neoplasms was mediated by extended cellular longevity. Evidence Rating Level: 1 (Excellent) Study Rundown: Telomere length is often predictive of the onset ....

Johns Hopkins University , Minute Medicine Inc , Rating Level , Telomere Length , Johns Hopkins Hospital Laboratories , Chronic Disease , Clonal Hematopoiesis , Extended Cellular Longevity , Long Telomere Syndrome , Pot1 Mutation ,