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University Health Network (UHN)

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Oncolytic virus plus immunotherapy extends survival in recurrent glioblastoma

The combination of intratumoral DNX-2401 and pembrolizumab appeared safe and provided “notable survival benefits” for select patients with recurrent glioblastoma, according to a study published in Nature Medicine.The phase 1/phase 2 trial did not meet its primary efficacy endpoint of objective response rate; however, the combination conferred a 12-month OS rate of 52.7% — which ....

Gelareh Zadeh , Farshad Nassiri , University Of Toronto , Krembil Brain Institute At Toronto Western Hospital , Princess Margaret Cancer Centre , Krembil Brain Institute , Toronto Western Hospital ,

Promising Results in Treatment for Recurrent Glioblastoma

Promising Results in Treatment for Recurrent Glioblastoma
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Clinical trial of a combination treatment shows great promise for patients with glioblastoma

A new international study published in Nature Medicine and presented as a late-breaking abstract at the American Association of Neurological Surgeons annual conference, shows great promise for patients with glioblastoma. ....

United States , Warren Mason , Emily Henderson , Farshad Nassiri , Gelareh Zadeh , American Association Of Neurological Surgeons , Princess Margaret Cancer Centre , University Health Network , University Of Toronto , Krembil Brain Institute , Nature Medicine , American Association , Neurological Surgeons , Senior Scientist , Princess Margaret Cancer , Wilkins Family , Brain Cancer , Clinical Trial ,

Glioblastoma treatment shows promising results and can extend survival

Glioblastoma treatment shows promising results and can extend survival
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