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 E-Mail IMAGE: Marked differences in gene activity were identified in the anterior portion of the hippocampus, which points downward toward the face, and the posterior, which points upward toward the back of... view more  Credit: Melissa Logies DALLAS - May 28, 2021 - A study of gene activity in the brain's hippocampus, led by UT Southwestern researchers, has identified marked differences between the region's anterior and posterior portions. The findings, published today in Neuron, could shed light on a variety of brain disorders that involve the hippocampus and may eventually help...

Study identifies the key genes in the brain involved in encoding memories UT Southwestern scientists have identified key genes involved in brain waves that are pivotal for encoding memories. The findings, published online this week in  Nature Neuroscience, could eventually be used to develop novel therapies for people with memory loss disorders such as Alzheimer’s disease and other forms of dementia. Making a memory involves groups of brain cells firing cooperatively at various frequencies, a phenomenon known as neural oscillations. However, explain study leaders Bradley C. Lega, M.D., a...

 E-Mail IMAGE: Above illustration shows a neuron (green) ensheathed by an oligodendrocyte (purple) with "activated " genetic material (DNA) in each cell's nucleus. Differences in each cell type's active DNA may underlie human... view more  Credit: Melissa Logies DALLAS - March 10, 2021 - UT Southwestern scientists have identified key genes involved in brain waves that are pivotal for encoding memories. The findings, published online this week in Nature Neuroscience, could eventually be used to develop novel therapies for people with memory loss disorders such as Alzheimer's diseas...

Credit: UT Southwestern Medical Center DALLAS - Feb. 3, 2021 - Inactivating a gene in young songbirds that's closely linked with autism spectrum disorder (ASD) prevents the birds from forming memories necessary to accurately reproduce their fathers' songs, a new study led by UT Southwestern shows. The findings, published online today in Science Advances, may help explain the deficits in speech and language that often accompany ASD and could eventually lead to new treatments specifically targeting this aspect of the disorder. Study leader Todd Roberts, Ph.D., associate professor of neuroscien...