Characterization of mutational "coldspots" in the cancer genome
Researchers at IRB Barcelona report mutation rate variation across the human genome. Regions with low mutation rates correlate with hypomethylation (low methyl
Source: newswise.com
Fran Supek News Today : Breaking News, Live Updates & Top Stories | Vimarsana
Stay updated with breaking news from Fran Supek. Get real-time updates on events, politics, business, and more. Visit us for reliable news and exclusive interviews.
Top News In Fran Supek Today - Breaking & Trending Today
Unearthing individual-level mutation risk patterns
Mutations, which occur continuously in every cell of our bodies, are a key contributor to cancer, ageing, and neurodegeneration.
Source: news-medical.net
Unravelling individual differences in DNA mutation risks
Researchers at IRB Barcelona discover unexpected patterns in mutation risks across individuals, uncovering 13 distinct genomic patterns.
Source: newswise.com
IRB scientists identify critical spots on the genome where gene editing could cause an unwanted response
CRISPR/Cas9 is a commonly used, very precise, gene editing technique whose development, by Jennifer A. Doudna and Emmanuelle Charpentier, was recognised with the 2020 Nobel Prize in Chemistry. Commonly known as "genetic scissors", CRISPR allows the introduction of the desired DNA sequence into (virtually) any spot of the genome, thus modifying or inactivating a gene. This technique is widely used in biomedical research and some CRISPR-based therapies are in clinical trials for the treatment of human blood disorders, some types of cancer and HIV, among other conditions.
Source: news-medical.net
Gene editing via CRISPR/Cas9 can lead to cell toxicity and genome instability
Gene editing via CRISPR/Cas9 can lead to cell toxicity and genome instability
Source: biotech-spain.com