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Adicet Bio Highlights ADI-001 Expansion, Persistence and Pharmacodynamic Profile from Ongoing Phase

ADI-001 showed robust dose-dependent expansion and persistence in patients with relapsed/refractory aggressive B-cell non-Hodgkin’s lymphoma (NHL)Strong exposure and persistence profile further supports Adicet’s allogeneic chimeric antigen receptor (CAR) T platform potential as best-in-classPharmacodynamic (PD) and. ....

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Adicet Bio Highlights ADI-001 Expansion, Persistence and Pharmacodynamic Profile from Ongoing Phase 1 Study at the 65th American Society of Hematology (ASH) Annual Meeting

ADI-001 showed robust dose-dependent expansion and persistence in patients with relapsed/refractory aggressive B-cell non-Hodgkin’s lymphoma

Strong exposure and persistence profile further. ....

United States , San Diego , Francesco Galimi , Monica Moreno , Drug Administration , Adicet Bio Inc , Adicet Bio , Chief Medical , Pharmacodynamic Profile , First In Class Allogeneic , Deltat Cell Therapy , Refractory Aggressiveb Cell Non Hodgkin , Early Phase , Investigational Therapies , Fast Track Designation , Private Securities Litigation Reform Act ,

Adicet Bio Highlights ADI-001 Expansion, Persistence and Pharmacodynamic Profile from Ongoing Phase 1 Study at the 65th American Society of Hematology (ASH) Annual Meeting

Adicet Bio Highlights ADI-001 Expansion, Persistence and Pharmacodynamic Profile from Ongoing Phase 1 Study at the 65th American Society of Hematology (ASH) Annual Meeting
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Adicet Bio Highlights ADI-001 Expansion, Persistence and Pharmacodynamic Profile from Ongoing Phase 1 Study at the 65th American Society of Hematology (ASH) Annual Meeting

Adicet Bio Highlights ADI-001 Expansion, Persistence and Pharmacodynamic Profile from Ongoing Phase 1 Study at the 65th American Society of Hematology (ASH) Annual Meeting
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United States , San Diego , Francesco Galimi , Contactsanne Bowdidge , Monica Moreno , Stern Investor Relations Inc , Drug Administration , Adicet Bio Inc , Chief Medical , Pharmacodynamic Profile , First In Class Allogeneic , Deltat Cell Therapy , Refractory Aggressiveb Cell Non Hodgkin , Early Phase , Investigational Therapies , Fast Track Designation , Adicet Bio , Private Securities Litigation Reform Act , Media Contactsanne , Investor Relations , Business Wire ,

Adicet Bio Reports Positive Data from Ongoing ADI-001 Phase 1 Trial in Patients with Relapsed or Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma (NHL)

ADI-001 demonstrated 71% overall response rate (ORR) and 63% complete response (CR) rate across all dose levels in patients with median 4 prior lines of therapy; 50% of patients enrolled had previously progressed on anti-CD19 chimeric antigen receptor T cell (CAR T) therapy

83% ORR and 67% CR rate observed in heavily pre-treated patients who had progressed on prior CAR T

Six-month CR rate consistent with autologous CAR T cell therapy

Favorable safety with no significant incidence of CRS (cytokine release syndrome) or ICANS (immune effector cell associated neurotoxicity syndrome)

Robust pharmacokinetic profile in dose level 4 (DL4) with Cmax and Day 28 persistence exceeding approved CD19 autologous CAR T therapy

Plan to transition ADI-001 program into potentially pivotal Phase 2 study in post-CAR T large B-cell lymphoma (LBCL) patients in first half of 2024

Clinical update from additional post-CAR T LBCL patients expected ....

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