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The global COVID-19 vaccination campaign saved an estimated 20 million lives. However, while current COVID-19 vaccines provide protection against developing severe disease, they do little to prevent infection and transmission.
<p>Findings published in the journal <em><a href="https://www.nature.com/articles/s41586-023-06951-3">Nature</a> </em>by physician-scientists at Beth Israel Deaconess Medical Center (BIDMC) and colleagues suggest that it may be possible to improve protection against COVID-19 by delivering the vaccine directly to the respiratory tract— the primary site of entry in SARS-CoV-2 infection.</p>
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Study supports continuing phase 3 trials of Ad26.COV2.S SARS-CoV-2 vaccine An international team of researchers has provided further evidence to confirm the immunogenicity and efficacy of a recombinant adenovirus vaccine currently being tested in phase 3 trials for its ability to protect against infection with severe acute respiratory coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19). The vaccine comprises a recombinant adenovirus serotype 26 (Ad26) vaccine vector expressing a stabilized form of the SARS-CoV-2 spike antigen that the virus uses to bind to...