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SONIA Trial Suggests Second-line Use May Be Optimal for CDK4/6 Inhibitors in HR+/HER2– Breast Cancer

The second line may be the optimal setting for patients with HR-positive, HER2-negative advanced breast cancer to receive CDK4/6 inhibitors plus an aromatase inhibitor followed by fulvestrant. ....

Gabes Sonke , Netherlands Cancer Institute , Functional Assessment , Cancer Therapy , European Quality , Life Five Dimension , Patients With Hr Positive , Her2 Negative , Cdk4 6 Inhibitors Plus An Aromatase Inhibitor Followed By Fulvestrant , Sonia Trial ,

You are special: The importance of identifying patients and their accompanying needs with metastatic breast cancer worldwide

You are special: The importance of identifying patients and their accompanying needs with metastatic breast cancer worldwide
plos.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from plos.org Daily Mail and Mail on Sunday newspapers.

United States , New South Wales , Noord Holland , Ikennad Ebuenyi , Gabes Sonke , Hildem Buiting , Phyllisn Butow , University Medical Center , University Of Amsterdam , University Of Pittsburgh , School Of Medical Psychology , Antoni Van Leeuwenhoek Netherlands Cancer Institute , American Society Of Clinical Oncology , Department Of Rehabilitation Science , American Society Of Clinical , University Of Sydney , Netherlands Cancer Institute , Palliative Care , Medical Center , Rehabilitation Science , Medical Psychology , American Society , Clinical Oncology , Clinical Oncology Meeting ,

Second-Line CDK4/6 Inhibitors May Be Preferred in Advanced Breast Cancer

First-line use of CDK4/6 inhibitors does not improve most outcomes when compared with second-line use in HR+, HER2- advanced breast cancer. ....

Noord Holland , Gabes Sonke , Netherlands Cancer Institute ,

First- vs. second-line CDK4/6 inhibitor use fails to benefit breast cancer subgroup

CHICAGO — First-line use of cyclin-dependent kinase 4/6 inhibitors did not confer significant benefit vs. second-line use when added to endocrine therapy for women with hormone receptor-positive, HER2-negative, advanced breast cancer.The findings, presented at ASCO Annual Meeting, suggested second-line cyclin-dependent kinase (CDK)4/6 inhibitors may be the preferred treatment option for ....

United States , Byjennifer Southall , Gabes Sonke , Mindy Valcarcel , Aditya Bardia , Dutch Health Insurers , Netherlands Organization For Health Research , Netherlands Cancer Institute , Netherlands Organization , Health Research ,