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Pembrolizumab plus gemcitabine and cisplatin improves survival in advanced biliary tract cancer

1. Median overall survival was greater in the pembrolizumab group compared to the control group (12.7 months vs. 10.9 months). 2. Treatment-related adverse events were comparable among patients in either group. Evidence Rating Level: 1 (Excellent) Study Rundown: Biliary tract cancers are a complex group of epithelial tumors with a poor prognosis. The first-line therapy ....

Eastern Cooperative Oncology Group , Rating Level , Advanced Endometrial , Between Oct , Advanced Biliary Tract Cancer , Biliary Tract Cancer , Gastrointestinal Cancer , Hepatocellular Carcinoma , Chronic Disease ,

Transcripts for CNN Fareed Zakaria GPS 20240604 14:55:00

serious side effects may include for starters, they come with in increases of gallstones and renal failure. use of drug in rodents during clinical trials led to an increase in thyroid cancer. these are risks that may be worth it for those suffering from serious medical conditions like obesity. but may not be for people just looking to have beach-ready bods by summer. the shots don t address the underlying drivers of america s obesity epidemic. they may be used to treat a disease, but attention should be given to prevention. they should encourage easier access to affordable and fresh produce and high quality proteins as well as wind down form subsidies that have made artificial sweetens like high fructose corn syrup in american diets. and as people brag on the internet about how the drugs have lessened their appetites ....

Side Effects , Renal Failure , Thyroid Cancer , United States , Obesity Epidemic , High Fructose Corn Syrup ,

Transcripts for CNN Fareed Zakaria GPS 20240604 17:54:00

Many users experienced a decrease in alcohol use, smoking, shopping and even nail biting while taking the drugs. scientists do not have a complete picture as to why these behaviors change in some people, but early reports suggest that it could be due to the drug s impact on the brain s reward pathways. addiction researchers have taken note. these drugs could be a real game changer. there s still a lot left to learn about how they work and what kind of long-term impact they may have. serious side effects may they come with an increased risk of pancreatitis, gallstones and renal failure, according to the prescribing information. use of the drug in rodents during clinical trials led to an increase in thyroid cancer. of course, these are risks that may be worth it for those suffering from serious medical conditions like obesity. may not be for people just looking to have beach-ready ....

Alcohol Use , Addiction Researchers , Reward Pathways , Game Changer , Side Effects , Renal Failure , Prescribing Information , Thyroid Cancer ,

Transcripts for BBCNEWS BBC News at One 20240604 12:22:00

Already signalled he wants to stand in the next westminster election. some may want to persuade him to change his mind. 0thers some may want to persuade him to change his mind. others may think leading plaid cymru at the moment is a bit of a poisoned chalice. there are huge challenges ahead detoxifying the party in the words of that report and persuading the electorate outside of plaid s heartland they are a party worth voting for, something you arguably adam price failed to do in his forehead a half years was like 0k, thank you, hywel griffith reporting there. hospitals in england have failed to hit a key target of eliminating 18 month waits for planned procedures like knee and hip replacements. new figures show that by the end of march, more than 10,000 people were still waiting that long, although nhs england says around 4,000 were complex cases or patients who had chosen to wait. 0ur health correspondent jim reed reports. summer, recovering from surgery in april, but she had to go ....

Westminster Election , Plaid Cymru , Adam Price , Party Worth , The End , Nhs England , Hip Replacements , Hywel Griffith Reporting , 0ur Health Correspondent , Jim Reed ,