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Gene Therapy Shows Potential for Repairing Damage Caused by Glaucoma and Dementia


Gene Therapy Shows Potential for Repairing Damage Caused by Glaucoma and Dementia
Source: Science photo library-ktsdesign/Getty Images
April 1, 2021
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Research by scientists at the University of Cambridge has demonstrated how gene therapy might help to repair some of the damage caused by chronic neurodegenerative conditions such as glaucoma and dementia. Their studies in rodents demonstrated how delivering two genes simultaneously using a single vector stimulated axonal transport in a humanized tauopathy model of Alzheimer’s disease, and in an experimental glaucoma model. Encouragingly, the results, reported in
Science Advances, showed “promising evidence” that the gene therapy might result in improvement in short-term memory in the tauopathy model of dementia. The team said the studies also highlight the potential effectiveness of gene therapy for treating complex polygenic conditions that have no single genetic cause. ....

United Kingdom , Keith Martin , Tasneem Khatib , University Of Cambridge , University Of Melbourne , John Van Geest Centre For Brain , Centre For Eye Research Australia , Centre For Brain Repair At Cambridge , Science Advances , Eye Research Australia , Brain Repair , Geest Centre , ஒன்றுபட்டது கிஂக்டம் , கேய்ட் மார்டின் , டஸ்னீம் கட்டிப் , பல்கலைக்கழகம் ஆஃப் கேம்பிரிட்ஜ் , பல்கலைக்கழகம் ஆஃப் மெல்போர்ன் , மையம் க்கு கண் ஆராய்ச்சி ஆஸ்திரேலியா , மையம் க்கு மூளை பழுது இல் கேம்பிரிட்ஜ் , கண் ஆராய்ச்சி ஆஸ்திரேலியா , மூளை பழுது ,