Study illustrates how cells choose DNA repair methods
DNA is usually regarded as the blueprint for life and is essential for an organism to perform biological tasks. A range of factors, including radical metabolite
Source: northkoreatimes.com
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Study illustrates how cells choose DNA repair methods
DNA is usually regarded as the blueprint for life and is essential for an organism to perform biological tasks
Source: webindia123.com
Study reveals how cells select DNA damage repair pathways
DNA is widely recognized as the blueprint for life, and it is required for an organism to assist biological functions
Source: webindia123.com
Study reveals how cells select DNA damage repair pathways
DNA is widely recognized as the blueprint for life, and it is required for an organism to assist biological functions. DNA may be damaged by a variety of
Source: organiser.org
How cells select DNA damage repair pathways
New research discovered a key protein that plays a role in DNA double-strand break repair. MSH2-MSH3, a mismatch repair protein, is recruited to DSB sites through the interaction with a chromatin remodeler SMARCAD1 and facilitates EXO1 recruitment for long-range DNA resection. This helps to promote homologous recombination over error-prone polymerase theta-mediated end-joining pathway to repair DSBs. The findings provide a deeper understanding of the mechanisms underlying DSB repair and may lead to new cancer treatments.
Source: eurekalert.org