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A team of scientists led by Dr Kei-ichi TAKATA from the Institute for Basic Science's Center for Genomic Integrity (CGI) discovered a new type of DNA repair mechanism that cancer cells use to recover from next-generation cancer radiation therapy.
A team of scientists has discovered a new type of DNA repair mechanism cancer cells use to recover from cancer radiation therapy damage.
A team of scientists led by Dr. Kei-ichi TAKATA from the Center for Genomic Integrity within the Institute for Basic Science (IBS), has discovered a new type of DNA repair mechanism that cancer cells use to recover from next-generation cancer radiation therapy.
Killing cancer cells without affecting surrounding normal cells is the most desirable approach for targeted cancer therapy. However, it cannot be easily achieved due to the similarities in the properties between normal and cancer cells.
E-Mail IMAGE: The background of the illustration is a photograph taken with the electron microscope showing DNA molecules decorated with MutS molecules, scanning the DNA for errors. The lower part shows... view more Credit: CNIO Scientists from the Genomic Integrity and Structural Biology Group led by Rafael Fernández-Leiro at the Spanish National Cancer Research Centre (CNIO) have discovered how certain proteins ensure the repair of errors introduced into the DNA during its replication. Using cryo-electron microscopy, they made the MutS protein, also known as the guardian of ou...