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Glycan analysis holds promise for early diagnosis of various cancers

In the future, a little saliva may be enough to detect an incipient cancer. Researchers at the University of Gothenburg have developed an effective way to interpret the changes in sugar molecules that occur in cancer cells. ....

Daniel-bojar , Lundberg-foundation , University-of-gothenburg , Cell-reports , Cancer , Fell , Glycan , Glycans , Olecule , Protein , Esearch , Spectrometer

How strep bacteria outsmart your immune system and why it matters for treatment

Researchers discover that Group A streptococcal infections alter immunoglobulin G (IgG) homeostasis to evade the immune system, affecting the transition from local to systemic infections. The study also raises concerns about the effectiveness of antibody-based therapies, as the bacteria's virulence factors can degrade therapeutic antibodies. ....

Jezper-shutterstock , Nature-communications , Antibodies , Ntibody , Bacteria , Glycan , Mmunoglobulin , Impetigo , N-vivo , Mass-spectrometry , Ortality , Necrotizing-fasciitis

Unlocking the power of lectins: BOA emerges as a potent weapon against all SARS-CoV-2 variants

Researchers discover that antiviral lectins like BOA can effectively inhibit SARS-CoV-2 and its variants by targeting spike glycans, opening doors for potential pan-coronavirus treatments. The study reveals that BOA's multivalent interactions make it a potent inhibitor against a range of viral variants, offering promise for future therapeutic strategies. ....

Kateryna-kon-shutterstock , Proceedings-of-the-national-academy-sciences , National-academy , Kateryna-kon , Coronavirus-disease-covid-19 , Ars , Ars-cov-2 , Arbohydrate , Oronavirus , Glycan , Glycans , Glycosylation