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VIDEO: Subunits B (blue), B-1 (cyan), and B-2 (gray) depicted as ribbon diagrams. Initially bound to B-1, subunit B unflattens, straining contact between subunits until they separate. The resulting loose lateral.
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Credit: Vilmos Zsolnay, University of Chicago.
Our cells are filled with bones, in a sense. Thin, flexible protein strands called actin filaments help support and move around the bulk of the cells of eukaryotes, which includes all plants and animals. Always on the go, actin filaments constantly grow, shrink, bind with other things, and branch off when cells move.
Supercomputer simulations have helped solve the mystery of how actin filaments polymerize, or chain together. This fundamental research could be applied to treatments to stop cancer spread, develop self-healing materials, and more. ....

United States , Gregory Voth , Stevenz Chou , Gregorya Voth , Vilmos Zsolnay , Thomasd Pollard , Harshwardhanh Katkar , Haigp Papazian Distinguished Service Professor , Yale University , Texas Advanced Computing Center , Multidisciplinary Research Initiative Grant , Department Of Biophysical Sciences , Proceedings Of The National Academy Sciences , University Of Chicago , Department Of Defense Army Research Office , University Of Chicago Research Computing Center , Voth Group , National Institute , National Academy , Biophysical Sciences , Distinguished Service Professor , Chicago Research Computing , Extreme Science , Engineering Discovery Environment , Texas Advanced Computing , Defense Army Research Office ,