Virologic Rebound Occurs in ~20 Percent Receiving Nirmatrelvir-Ritonavir
Virologic rebound more common among those who started therapy within 2 days of symptom onset
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Virologic rebound more common among those who started therapy within 2 days of symptom onset
<p>A new study by investigators from <a href="https://www.massgeneralbrigham.org/">Mass General Brigham</a> found that one in five individuals taking Nirmatrelvir-ritonavir therapy, commonly known as Paxlovid, to treat severe symptoms of COVID-19, experienced a positive test result and shedding of live and potentially contagious virus following an initial recovery and negative test—a phenomenon known as virologic rebound. By contrast, people not taking Paxlovid only experienced rebound about 2 percent of the time. Results are published in <a href="...
At a glance: New study shows that viral rebound with Paxlovid is more common than previously believed. Clinicians should counsel patients about the possible risk of transmitting virus during rebound. A new study by Harvard Medical School researchers at Massachusetts General Hospital and Brigham and Women’s Hospital has found that one in five individuals […]