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Researchers hope the likely explanation for the improved survival rate of mesothelioma can be used to treat other cancers.
The study reports the interaction of BAP1, HMGB1 and HDAC1 form a trimer, a macromolecular component.
December 17, 2020 Postdoctoral research fellow and collaborator Angela Bononi in Carbone’s lab. Update: In February 2021, the paper was selected as Paper of the Month by the National Institute of Environmental Health Sciences. New research has found that individuals born with inherited mutations of the ‘ BLM gene’ are more susceptible to developing mesothelioma, especially upon exposure to asbestos. The study was conducted by University of Hawaiʻi Cancer Center researcher Michele Carbone and collaborators, and was published in the Proceedings of the National Academy of Sciences. Indi...
Posted: Dec 17, 2020 Michele Carbone New research has found that individuals born with inherited mutations of the ‘BLM gene’ are more susceptible to developing mesothelioma, especially upon exposure to asbestos. The study was conducted by University of Hawaiʻi Cancer Center researcher Michele Carbone and collaborators, and was published in the Proceedings of the National Academy of Sciences. Individuals who inherit two mutated copies of the BLM gene are affected by the rare Bloom Syndrome, characterized by short stature, a red rash over the nose and cheeks, mild immune deficiency and an...