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Researchers from the University of Hawaiʻi Cancer Center, led by Dr. Haining Yang and Dr. Michele Carbone, have discovered the critical role of the HMGB1 protein in asbestos-induced mesothelioma.
Published in the Sept. 18 issue of the Proceedings of the National Academy of Sciences of the U.S., the research revealed following asbestos exposure the release of HMGB1 to the human body kick-starts an inflammatory process, which over time promotes mesothelioma.
The HMGB1 protein plays a critical role in the development of asbestos-induced mesothelioma.
Mesothelioma is a rare, aggressive and deadly cancer of the mesothelial tissue lining the internal organs and is incurable in most of the cases.
Patients diagnosed with mesothelioma typically only live for one to two years — but that timeline could change with recent findings.