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Billionaire investor Bill Ackman blamed US foreign-policy failures for the brutal conflict, while Chamath Palihapitiya predicted the violent clash would lift oil prices.
The Federal Reserve has a complicated decision to make during its next policy meeting, which is only a few weeks away.
The yield on the 10-year US Treasury jumped to 4.8% before easing slightly as investors digested September's hot jobs report.
Gold is facing tough competition this year as the preferred haven for cautious investors.
The US labor market surged in September, blowing expectations out of the water by adding 336,000 jobs, according to Bureau of Labor Statistics data released Friday.