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Scientists develop new organoid model to stud

<p>Researchers from the Organoid group have developed a new organoid model that can be used to study the thymus. The organoids, derived from mouse thymus tissue, specifically model thymic epithelial cells (TECs). These cells are responsible for training the T cells of the immune system to properly respond to pathogens. It is the first laboratory model that enables long-term culture of TECs, which presents new opportunities to study their function. Ultimately, this could also bring new insights into the treatment of patients with impaired thymus function. The study was published in Cell Reports on 27 March 2024.</p>
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Harry Begthel , Hong Gyun Lee , Hans Clevers , Jeroen Korving , Sam Willemsen , Developmentat Roche , Amanda Andersson Rolf , Wisma Eka Yanti , Hubrecht Institute , Pharma Research , Method Of Research , Royal Netherlands Academy Of Arts , Hubrecht Institute For Developmental Biology , Utrecht University , Early Development , Stem Cell Research , European Molecular Biology Laboratory , Head Of Pharma Research , Cell Reports , Sangho Lim , Developmental Biology , Molecular Genetics , Royal Netherlands Academy , Utrecht Science , Early Developmentat Roche ,

Roche launches Institute of Human Biology to accelerate breakthroughs in R&D by unlocking the potential of human model systems

Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today the launch of the Institute of Human Biology (IHB) focussing on advancing research in the field of human model systems such as organoids. Leveraging human model systems, the institute aims to accelerate drug discovery and development by improving the understanding . ....

Matthias Lutolf , Hans Clevers , Early Development , Head Of Pharma Research , Institute Of Human Biology , Human Biology , Pharma Research ,