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 E-Mail Extra funding should be made available for early years care in the wake of the pandemic, researchers say. Experts at the University of Leeds, University of Oxford and Oxford Brookes University have made the call after assessing the benefits of early childhood education and care (ECEC) for children under three during COVID-19. They found children who attended childcare outside the home throughout the first UK lockdown made greater gains in language and thinking skills, particularly if they were from less advantaged backgrounds. And now they are making several policy recommendations in...

 E-Mail IMAGE: Electrical recordings from glia-like supporting cell (GLS) of cochlea. Knock-in (KI) mouse with TMEM43-p.(Arg372Ter) variant exhibits disruption of GLS K+ conductance. Grey; control mice, cyan; heterozygous KI mice, purple; homozygous... view more  Credit: Institute for Basic Science Hearing loss is a disability that affects approximately 5% of the world's population. Clinically determining the exact site of the lesion is critical for choosing a proper treatment for hearing loss. For example, the subjects with damage in sound conduction or mild outer hair cell damage ...

 E-Mail Finnish researchers have been the first to determine the cause for the nonsyndromic early-onset hereditary canine hearing loss in Rottweilers. The gene defect was identified in a gene relevant to the sense of hearing. The study can also promote the understanding of mechanisms of hearing loss in human. Hearing loss is the most common sensory impairment and a complex problem in humans, with varying causes, severity and age of onset. Deafness and hearing loss are fairly common also in dogs, but gene variants underlying the hereditary form of the disorder are so far poorly known. Resea...

 E-Mail CORVALLIS, Ore. - Researchers at Oregon State University have found a key new piece of the puzzle in the quest to use gene therapy to enable people born deaf to hear. The work centers around a large gene responsible for an inner-ear protein, otoferlin. Mutations in otoferlin are linked to severe congenital hearing loss, a common type of deafness in which patients can hear almost nothing. "For a long time otoferlin seemed to be a one-trick pony of a protein," said Colin Johnson, associate professor of biochemistry and biophysics in the OSU College of Science. "A lot of genes will find...

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