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Trastuzumab Deruxtecan Demonstrates Efficacy Reducing Brain Metastases in HER2m NSCLC

Regardless of presence of brain metastases, patients with HER2-mutant (HER2m) non–small cell lung cancer (NSCLC) showed systemic responses to trastuzumab deruxtecan. In addition, the therapy showed intracranial efficacy to reduce the size of brain metastases. ....

United States , France General , Jessica Lin , Institut Gustave Roussy , David Planchard , Harvard Medical School , Henri Belinda Termeer Center , Department Of Cancer Medicine , Cancer Medicine , Massachusetts General Hospital , Thoracic Cancers , Targeted Therapies , Esmo Congress , Trastuzumab Deruxtecan , Antibody Drug Conjugate , Non Small Cell Lung Cancer ,