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Timing Is Everything: CAR T for Follicular Lymphoma

CAR T-cell therapy is the best option for patients with relapsed/refractory follicular lymphoma, even though it comes with serious side effects. ....

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US FDA Mandates Label Updates on CAR-T Cancer Therapies

The U.S. Food and Drug Administration said on Thursday cancer therapies that use CAR-T technology will require changes to the so-called "boxed warning" to highlight the. ....

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Abecma Approved for Earlier Lines in R/R Multiple Myeloma

The drug manufacturers report a complete response rate of 39% with idecabtagene vicleucel (Abecma) vs 5% with standard regimens. ....

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CAR T Cell: Do Benefits Still Outweigh Risks?

Despite concerns about the development of secondary T-cell malignancies due to CAR T-cell immunotherapy, experts still believed that the benefits outweigh the risks. ....

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Infection Main Cause of Nonrelapse Death With CAR T Therapy

Infections, cardiopulmonary disease, and second cancers were among the leading causes of nonrelapse deaths in patients receiving CAR T-cell therapy, both in clinical trials and clinical practice. ....

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