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Press release content from Globe Newswire. The AP news staff was not involved in its creation. ChemoCentryx and VFMCRP Provide Topline Results from ACCOLADE Trial of Avacopan in C3 ... ChemoCentryx, Inc.December 21, 2020 GMT As in ANCA vasculitis, avacopan demonstrated statistically significant improvement in renal function as measured by eGFR compared to placebo over 26 weeks of blinded treatment The change from baseline to Week 26 in C3 Glomerulopathy Histologic Index (C3G HI) for Disease Activity (primary endpoint) was not statistically different between the two treatment groups, while the...

Share: As in ANCA vasculitis, avacopan demonstrated statistically significant improvement in renal function as measured by eGFR compared to placebo over 26 weeks of blinded treatment The change from baseline to Week 26 in C3 Glomerulopathy Histologic Index (C3G HI) for Disease Activity (primary endpoint) was not statistically different between the two treatment groups, while the C3G HI for Disease Chronicity (measuring progression of fibrosis) shows significant benefit for avacopan versus placebo Avacopan safe and well tolerated in C3G patients ChemoCentryx and VFMCRP plan to discuss registr...