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Repurposed Protease Regulates Key Signaling Protein

Repurposed Protease Regulates Key Signaling Protein
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Fangfang Lu , Yingdi Wang , Chia Hsueh Lee , Hongtu Zhao , Matthew Freeman , Yaxin Dai , Jude Department Of Structural Biology , Wellcome Trust Investigator , University Of Oxford , National Institutes Of Health , Jude Children Research Hospital , Molecular Cell , Jude Children , Research Hospital , Jude Department , National Institutes , Wellcome Trust Investigator Awards ,

Repurposed protease controls important signaling molecule-activating protein

Efficient communication between cells is vital for many biological processes, such as recruiting immune cells to combat disease. The rapid release of at least 80 signaling molecules, including tumor necrosis factor and epidermal growth factor, is controlled by a membrane-bound protease called ADAM17. ....

Hongtu Zhao , Yingdi Wang , Yaxin Dai , Matthew Freeman , Chia Hsueh Lee , Fangfang Lu , University Of Oxford , Jude Department Of Structural Biology , Jude Children Research Hospital , Jude Department , Structural Biology , Jude Children , Research Hospital , Molecular Cell ,

Research reveals surprising inactivation mechanism for voltage-gated ion channel

Research reveals surprising inactivation mechanism for voltage-gated ion channel
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Yaxin Dai , Chia Hsueh Lee , Yingdi Wang , Hongtu Zhao , Lily Yeh Jan , Jude Children Research Hospital , National Institutes Of Health , University Of California San Francisco , Howard Hughes Medical Institute , Jude Children , Research Hospital , California San , Jude Structural , National Institutes , Molecular Cell ,