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Iptacopan Reduces Proteinuria, Demonstrates Benefit in C3 Glomerulopathy

In the APPEAR-C3G trial, iptacopan reduced proteinuria by 35.1% in patients with C3 glomerulopathy, with Novartis planning regulatory submissions for C3G before the end of 2024. ....

G Steering Committee Member David Kavanagh , European Renal Association Congress , Foundation Trust David Kavanagh , Faculty Of Medical Sciences At Newcastle University , David Kavanagh , Steering Committee Member David Kavanagh , Complement Therapeutics , Honorary Consultant Nephrologist , Medical Sciences , European Renal Association ,

David Kavanagh, MBChB, PhD: Iptacopan Offers Hope for C3 Glomerulopathy

A Q&A with David Kavanagh, MBChB, PhD, on the results of the APPEAR-C3G trial and implications for care moving forward. ....

David Kavanagh , European Renal Association Congress , Faculty Of Medical Sciences At Newcastle University , Foundation Trust David Kavanagh , Complement Therapeutics , Honorary Consultant Nephrologist , Medical Sciences , European Renal Association ,

Novartis presents latest Phase III Fabhalta® (iptacopan) data in C3 glomerulopathy (C3G) showing clinically meaningful and statistically significant 35.1% proteinuria reduction vs. placebo

Secondary endpoint data for estimated glomerular filtration rate (eGFR) showed numerical improvement over 6 months vs. placebo1; additional 6-month open-label. ....

Czech Republic , United States , Parag Mahanti , David Soergel , Prnewswire Novartis , Marianne Silkj , Marlena Abdinoor , Jonathan Graham , David Kavanagh , Sloan Simpson , Faculty Of Medical Sciences At Newcastle University , University Of Washington , G Steering Committee Member , Metabolism Development Unit , European Renal Association , Novartis Pharmaceuticals Corporation , Exchange Commission , Glomerular Diseases Work Group , Professor David Kavanagh , Complement Therapeutics , Honorary Consultant Nephrologist , Medical Sciences , Newcastle University , Steering Committee , Global Head , Parallel Group ,

Novartis presents latest Phase III Fabhalta® (iptacopan) data in C3 glomerulopathy (C3G) showing clinically meaningful and statistically significant 35.1% proteinuria reduction vs. placebo

Novartis presents latest Phase III Fabhalta® (iptacopan) data in C3 glomerulopathy (C3G) showing clinically meaningful and statistically significant 35.1% proteinuria reduction vs. placebo
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United States , Czech Republic , Imke Kappes , Jonathan Graham , Marlena Abdinoor , David Kavanagh , Nicole Zinsli Somm , Parag Mahanti , Marianne Silkj , Satoshi Sugimoto , David Soergel , Isabella Zinck , Sloan Simpson , Michael Meo , Exchange Commission , University Of Washington , Metabolism Development Unit , Faculty Of Medical Sciences At Newcastle University , European Renal Association , Glomerular Diseases Work Group , G Steering Committee Member , Professor David Kavanagh , Complement Therapeutics , Honorary Consultant Nephrologist , Medical Sciences , Newcastle University ,

Novartis Pharma AG: Novartis presents latest Phase III Fabhalta® (iptacopan) data in C3 glomerulopathy (C3G) showing clinically meaningful and statistically significant 35.1% proteinuria reduction vs. placebo

Secondary endpoint data for estimated glomerular filtration rate (eGFR) showed numerical improvement over 6 months vs. placebo1; additional 6-month open-label data to be presented at a future medical meeting2 ....

United States , Czech Republic , Imke Kappes , Marlena Abdinoor , David Soergel , Michael Meo , Sloan Simpson , Jonathan Graham , Parag Mahanti , Isabella Zinck , Marianne Silkj , David Kavanagh , Nicole Zinsli Somm , Satoshi Sugimoto , Faculty Of Medical Sciences At Newcastle University , Glomerular Diseases Work Group , Metabolism Development Unit , Exchange Commission , European Renal Association , G Steering Committee Member , University Of Washington , Professor David Kavanagh , Complement Therapeutics , Honorary Consultant Nephrologist , Medical Sciences , Newcastle University ,