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New Study: Gene Therapy Can Effectively Eliminate HIV Infection

Researchers from Temple University and UNMC collaborate in a study recently published in the journal Proceedings of the National Academy of Sciences. Gene-editing therapy targeting both HIV-1, the virus responsible for AIDS, and CCR5, the co-receptor assisting viral entry into cells, has been de

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Chances of eliminating HIV infection increased by novel dual gene-editing approach

Chances of eliminating HIV infection increased by novel dual gene-editing approach
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HIV eliminated in mice in new study

The possibility of using gene-editing to eliminate HIV is growing stronger, according to a group of researchers who have successfully combined gene-editing with antiretroviral drugs to cure animals of HIV — a feat they have now pulled off more than once.

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HIV research: In search for a cure, Temple University researchers say new gene-editing strategy may be a game-changer

Scientists say HIV can be eliminated from the body by using a new gene-editing therapy that targets the virus and the molecule that allows it to invade cells. Researchers at Temple University and the University of Nebraska Medical Center combined that approach with antiretroviral drugs in a study on mice.

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Dual CRISPR Gene Editing Strategy Cures Animals of HIV-1

Researchers say dual CRISPR approach in combination with ART achieved effective HIV-1 elimination in humanised mice and has potential for translation to the clinic

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Chances of eliminating HIV infection increase

EMBARGO UNTIL: May 1, 2023 at 3 PM ET
Gene-editing therapy aimed at two targets – HIV-1, the virus that causes AIDS, and CCR5, the co-receptor that helps the virus get into cells – can effectively eliminate HIV infection, new research from the Lewis Katz School of Medicine at Temple University and the University of Nebraska Medical Center (UNMC) shows. The study, published online in the journal The Proceedings of the National Academy of Sciences (PNAS), is the first to combine a dual gene-editing strategy with antiretroviral drugs to cure animals of HIV-1.

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10 Inspiring Stories from the Fight against HIV

Living through a global pandemic, it can seem like the news has slipped into an endless cycle of misery and despair. But it is important to remember that

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NIH Avant Garde Award for out-of-box, innovative concept to cure HIV and treat addiction

Credit: UMSOM
University of Maryland School of Medicine (UMSOM) Professor of Diagnostic Radiology & Nuclear Medicine, Linda Chang, MD, MS, received the National Institute on Drug Abuse (NIDA) 2021 Avant Garde Award (DP1) for HIV/AIDS and Substance Use Disorder Research -- a National Institutes of Health (NIH) Director's Pioneer Award. This prestigious award supports researchers with exceptional creativity, who propose high-impact research with the potential to be transformative to the field. Her proposed project will involve a team of experts in brain imaging, infectious diseases, addiction, animal research, and gene-editing technology with the goal to essentially eradicate all traces of HIV from the body, and treat commonly co-existing substance use disorders. 2021 Avant Garde Awardees are expected to receive more than $5 million over five years.

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New Evidence COVID-19 Invades the Brain

New Evidence COVID-19 Invades the Brain
medscape.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medscape.com Daily Mail and Mail on Sunday newspapers.

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