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Form DEFC14A Forte Biosciences, Inc Filed by: Camac Fund, LP
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Metacrine (MTCR) Reports Target Patient Enrollment Achieved for MET642 Phase 2a Trial Interim Analysis
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Metacrine to Present Final Results from Phase 1 Trial of MET642, an Optimized FXR Agonist, at .
Metacrine, Inc.March 11, 2021 GMT
SAN DIEGO, March 11, 2021 (GLOBE NEWSWIRE) Metacrine, Inc. (Nasdaq: MTCR), a clinical-stage biopharmaceutical company focused on discovering and developing differentiated therapies for patients with liver and gastrointestinal diseases, today announced that final results from the company’s Phase 1 trial of MET642, a farnesoid X receptor (FXR) agonist in development for the treatment of non-alcoholic steatohepatitis (NASH), will be presented as a distinguished abstract at the 2021 NASH-TAG Conference. The conference is taking place March 11-13, 2021 in Park City, Utah and virtually on-line.
Metacrine Reports Positive Results from Phase 1 Trial of MET642
MET642 Demonstrated Sustained Pharmacokinetic Profile and Robust FXR Target Engagement with Once-Daily Oral Dosing, without Pruritis or LDL-Cholesterol Increase
Doses Selected for Phase 2a Trial in Patients with NASH; On-Track to Initiate in 1H21
SAN DIEGO, Dec. 17, 2020 (GLOBE NEWSWIRE) Metacrine, Inc. (Nasdaq: MTCR), a clinical-stage biopharmaceutical company focused on discovering and developing differentiated therapies for patients with liver and gastrointestinal diseases, today reported preliminary results from its Phase 1 trial of MET642, a farnesoid X receptor (FXR) agonist being developed for the treatment of non-alcoholic steatohepatitis (NASH) and inflammatory bowel disease. Findings show that treatment with MET642 was safe and generally well-tolerated and demonstrated a sustained pharmacokinetic (PK) profile and robust FXR target engagement after 14 days of daily oral dosing in healthy volunteers.