Proteomic-Based Cell Map Offers Ultra-Detailed Look at Cellular Organization
A BioID proximity map of the proteome provides an ultra-detailed look at the organization of a human cell by defining the locations of 4,145 proteins.
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A BioID proximity map of the proteome provides an ultra-detailed look at the organization of a human cell by defining the locations of 4,145 proteins.
Researchers from Sinai Health have published a study providing an ultra-detailed look at the organization of a living human cell, providing a new tool that can help scientists around the world better understand what happens during disease. The new study, published in the journal Nature, was conducted in the laboratory of Dr. Anne-Claude Gingras, a senior investigator at the Lunenfeld-Tanenbaum Research Institute and professor in the Department of Molecular Genetics at the University of Toronto.
By Bill Hathaway May 25, 2021 Share this with FacebookShare this with TwitterShare this with LinkedInShare this with EmailPrint this (Illustration by Michael S. Helfenbein) The primary function of the lung is to facilitate transfer of oxygen to the blood stream. Crucial to this lifegiving task are endothelial cells, which line blood vessels permeating the lung and through which gas exchange occurs. Malfunction of these cells is implicated in a range of different diseases, including COPD (chronic obstructive pulmonary disease), pulmonary fibrosis, and pulmonary hypertension. And the COVID-19 p...
A reference map of endothelial cells in the lungs was created to help researchers identify specific abnormalities that occur in a host of lung diseases
E-Mail The largest study of its type in the UK has identified differences in the immune response to COVID-19, between people with no symptoms, compared to those suffering a more serious reaction to the virus. Researchers from the Wellcome Sanger Institute, Newcastle University, University College London, University of Cambridge, EMBL's European Bioinformatics Institute (EMBL-EBI) and their collaborators within the Human Cell Atlas initiative, found raised levels of specific immune cells in asymptomatic people. They also showed people with more serious symptoms had lost these protective cel...