Vital Signs Digital Law Health Update | Winter 2023
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We bring you Vital Signs, a curated, one-stop resource on the most notable digital health law updates from our U.S. and…
Innovation for impact: delivering results for the rural poor
MIT research shows that in people carrying the APOE4 risk variant, a key brain cell type mismanages cholesterol needed to insulate neurons properly — another sign that APOE4 contributes to Alzheimer's disease by disrupting lipids in the brain.
When people carry the Alzheimer's associated APOE4 gene, oligodendrocytes fail to transport fatty molecules to wrap neurons that make brain circuitry connections. This deficit of myelin may contribute to the pathology and symptoms of Alzheimer's disease.
A gene recognized as the strongest risk factor for Alzheimer's disease (AD) alters the way cholesterol moves around the brain and as we age, this altered movement likely contributes to loss of learning and memory, a team of researchers from the Icahn School of Medicine at Mount Sinai and the Massachusetts Institute of Technology reports.