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Study suggests key to antipsychotic drug-induced obesity

An increased concentration of the hormone leptin in fat cells is believed to be responsible for weight gain associated with antipsychotic drugs, according to re ....

United States , Chen Liu , Xue Nan Sun , Joelk Elmquist , Qingzhang Zhu , Jan Bernd Funcke , Chao Li , Shangang Zhao , Stevenc Wyler , Christinem Kusminski , Carlh Westcott , Philipp Scherer , Shiuhwei Chen , Peter Odonnell Jr , Roya Brinkley , Jyun Wang , Qian Lin , Voelcker Fund Young Investigator Pilot Award , Research Institute Of Texas , Minnie Tomerlin Voelcker Fund , Southwestern Nutrition Obesity Research Center , Brain Institute , American Heart Association , Doh Lab , Southwestern Medical Center , Hypothalamic Research ,

Study suggests key to antipsychotic drug-induced obesity

An increased concentration of the hormone leptin in fat cells is believed to be responsible for weight gain associated with antipsychotic drugs, according to re ....

United States , Shangang Zhao , Stevenc Wyler , Christinem Kusminski , Carlh Westcott , Xue Nan Sun , Chen Liu , Joelk Elmquist , Jan Bernd Funcke , Qingzhang Zhu , Chao Li , Peter Odonnell Jr , Roya Brinkley , Jyun Wang , Qian Lin , Philipp Scherer , Shiuhwei Chen , Doh Lab , Southwestern Medical Center , American Heart Association , Diabetes Research , Hypothalamic Research , Senior Research , Touchstone Center , National Institutes Of Health , National Institute Of Diabetes ,

UTSW scientists discover a possible strategy to combat obesity

UT Southwestern scientists may have identified a method of safely mimicking the weight-loss benefits of a plant compound that – despite its harmful side effects – hold critical answers to developing therapies for obesity. ....

United States , Peter Odonnell Jr , Kevinw Williams , Emily Henderson , Centers For Disease , Brain Institute , National Institutes Of Health , Ut Southwestern Center , Drug Administration , Hypothalamic Research , Disease Control , National Institutes , Associate Professor , Internal Medicine , Petero Donnell , Blood Pressure , High Blood Pressure , Weight Loss ,

Scientists Find cause of Antipsychotic-induced Weight Gain

Scientists identified the molecular mechanism that can cause weight gain for those using a common antipsychotic medication. ....

Chen Liu , Utsw Odonnell Brain Institute , Hypothalamic Research Center , Drug Administration , Weight Loss Program , Odonnell Brain Institute , Hypothalamic Research , Its Link , Prevent Childhood Obesity , Vigorous Physical , Zone Diet , Bulgediabetes Type , Sugar Sweetened Beveragesmantra , Vigorous Physical Activityquiz , Weight Lossdrugs Causing , Weight Gain , Antipsychotic Medication , Experimental Medicine , Science And Technology , Appetite Control , சென் லியூ , எடை இழப்பு ப்ரோக்ர்யாம் , டோனெல் மூளை நிறுவனம் , அதன் இணைப்பு , ப்ரிவெஂட் குழந்தை பருவம் உடல் பருமன் , ஸோந் உணவு ,

Scientists identify source of weight gain from antipsychotics

Credit: UT Southwestern Medical Center
DALLAS - May 12, 2021 - Scientists with UT Southwestern s Peter O Donnell Jr. Brain Institute have identified the molecular mechanism that can cause weight gain for those using a common antipsychotic medication. The findings, published in the
Journal of Experimental Medicine, suggest new ways to counteract the weight gain, including a drug recently approved to treat genetic obesity, according to the study, which involved collaborations with scientists at UT Dallas and the Korea Advanced Institute of Science and Technology.
If this effect can be shown in clinical trials, it could give us a way to effectively treat patients for their neuropsychiatric conditions without this serious side effect, says lead author Chen Liu, Ph.D., assistant professor of internal medicine and neuroscience, and with UTSW s O Donnell Brain Institute and Hypothalamic Research Center. ....

South Korea , United States , Amandag Arnold , Sharig Birnbaum , Lin Jia , Stevenc Wyler , Xiameng Chen , Peter Odonnell Jr , Xiujuan Li , Eun Seon Yoo , Chen Liu , Brain Institute , Korean National Research Foundation , National Institutes Of Health , Utsw Odonnell Brain Institute , Hypothalamic Research Center , Drug Administration , Korea Advanced Institute Of Science , Petero Donnell , Experimental Medicine , Korea Advanced Institute , Odonnell Brain Institute , Hypothalamic Research , National Institutes , Rong Wan , Jong Woo Sohn ,