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Researchers develop a transferrable and integrative type I CRISPR-based platform to edit superbugs

Researchers develop a transferrable and integrative type I CRISPR-based platform to edit superbugs
A research team led by Dr Aixin YAN, Associate Professor from the Research Division for Molecular & Cell Biology, Faculty of Science, in collaboration with Honorary Clinical Professor Patrick CY WOO from the Department of Microbiology, Li Ka Shing Faculty of Medicine, the University of Hong Kong (HKU), reported the development of a transferrable and integrative type I CRISPR-based platform that can efficiently edit the diverse clinical isolates of
Pseudomonas aeruginosa, a superbug capable of infecting various tissues and organs and a major source of nosocomial infections.
The technique can accelerate the identification of resistance determinants of multidrug resistant (MDR) pathogens and the development of novel anti-resistance strategies. ....

Aixin Yan , Li Ka Shing , Emily Henderson , Department Of Microbiology , University Of Hong Kong , Nucleic Acids Research , Research Division For Molecular Cell Biology , Associate Professor , Research Division , Cell Biology , Honorary Clinical Professor Patrick , Hong Kong , Nucleic Acids , Queen Mary , Cell Reports , If Cascade , If Cascade Mediated , லி கா ஷிங் , எமிலி ஹென்டர்சன் , துறை ஆஃப் நுண்ணுயிரியல் , பல்கலைக்கழகம் ஆஃப் ஹாங் காங் , இணை ப்ரொஃபெஸர் , ஆராய்ச்சி பிரிவு , செல் உயிரியல் , ஹாங் காங் , ராணி மேரி ,

Scientists harness naturally abundant CRISPR-Cas system to edit superbugs

Date Time
Scientists harness naturally abundant CRISPR-Cas system to edit superbugs
An illustration of the strategies and workflow of the transferrable type I CRISPR Cascade-mediated editing of the superbug P. aeruginosa.
A research team led by Dr Aixin YAN, Associate Professor from the Research Division for Molecular & Cell Biology, Faculty of Science, in collaboration with Honorary Clinical Professor Patrick CY WOO from the Department of Microbiology, Li Ka Shing Faculty of Medicine, the University of Hong Kong (HKU), reported the development of a transferrable and integrative type I CRISPR-based platform that can efficiently edit the diverse clinical isolates of Pseudomonas aeruginosa, a superbug capable of infecting various tissues and organs and a major source of nosocomial infections. The technique can accelerate the identification of resistance determinants of multidrug resistant (MDR) pathogens and the development of novel anti-resistance strategies. ....

Hong Kong , University Of Hong Kong , Hong Kong General , Aixin Yan , Li Ka Shing , Research Grants Council Of Hong Kong , Nucleic Acids Research , Research Division For Molecular Cell Biology , China Agricultural University , School Of Biological Sciences , Department Of Microbiology , Dr Meiru Si Qufu Normal University , Seed Fund For Basic Research , Research Fund , Associate Professor , Research Division , Cell Biology , Honorary Clinical Professor Patrick , Nucleic Acids , Queen Mary , Cell Reports , If Cascade , If Cascade Mediated , Biological Sciences , Postdoctoral Fellow , South China Agricultural University ,

HKU scientists harness the naturally abundant CRISPR-Cas system to edit superbugs with the hope of treating infections caused by drug resistant pathogens

HKU scientists harness the naturally abundant CRISPR-Cas system to edit superbugs with the hope of treating infections caused by drug resistant pathogens
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

Hong Kong , University Of Hong Kong , Hong Kong General , Aixin Yan , Li Ka Shing , Research Grants Council Of Hong Kong , Nucleic Acids Research , Research Division For Molecular Cell Biology , China Agricultural University , School Of Biological Sciences , Department Of Microbiology , Dr Meiru Si Qufu Normal University , Seed Fund For Basic Research , Research Fund , Associate Professor , Research Division , Cell Biology , Honorary Clinical Professor Patrick , Nucleic Acids , Queen Mary , Cell Reports , If Cascade , If Cascade Mediated , Biological Sciences , Postdoctoral Fellow , South China Agricultural University ,

Scientists harness naturally abundant CRISPR-Cas system to edit superbugs with hope of treating infections caused by drug resistant

Scientists harness naturally abundant CRISPR-Cas system to edit superbugs with hope of treating infections caused by drug resistant
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

Aixin Yan , Li Ka Shing , Department Of Microbiology , University Of Hong Kong , Nucleic Acids Research , Research Division For Molecular Cell Biology , Associate Professor , Research Division , Cell Biology , Honorary Clinical Professor Patrick , Hong Kong , Nucleic Acids , Queen Mary , Cell Reports , If Cascade , If Cascade Mediated , லி கா ஷிங் , துறை ஆஃப் நுண்ணுயிரியல் , பல்கலைக்கழகம் ஆஃப் ஹாங் காங் , இணை ப்ரொஃபெஸர் , ஆராய்ச்சி பிரிவு , செல் உயிரியல் , ஹாங் காங் , ராணி மேரி , செல் அறிக்கைகள் ,