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New insights into immune responses to malaria


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New insights into immune responses to malaria
Advanced technologies have been used to solve a long-standing mystery about why some people develop serious illness when they are infected with the malaria parasite, while others carry the infection asymptomatically.
Dr Lisa Ioannidis (left) and Associate Professor Diana
Hansen (right) have led a study into why some people
develop serious illness as a result of malaria infections.
An international team used mass cytometry – an in-depth way of characterising individual cells – and machine learning to discover ‘immune signatures’ associated with symptomatic or asymptomatic infections in people infected with the Plasmodium vivax parasite. This uncovered an unexpected role for immune T cells in protection against malaria, a finding that could help to improve the development of much-needed malaria vaccines. ....

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UK and Indonesia unite to tackle challenges around delivering Covid-19 vaccines


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UK and Indonesia unite to tackle challenges around delivering Covid-19 vaccines
An Anglo-Indonesian research consortium that unites the countries’ leading experts to tackle global challenges including pandemics, food security and climate change is to host the UK-Indonesia Interdisciplinary Sciences Forum to discuss effective strategies for Covid-19 vaccination programmes.
The online forum being facilitated by the UK Indonesia Consortium for Interdisciplinary Sciences (UKICIS), led by the University of Nottingham, in collaboration with the University of Warwick, Coventry University, and three Indonesian leading universities Institut Teknologi Bandung, IPB University, Universitas Gadjah Mada and the Embassy of the Republic of Indonesia, will gather experts from both the UK and Indonesia to share challenges and successes from the two countries in delivering vaccines to a combined population of more than 300 million people. ....

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