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The European royal, 51, joined her husband King Felipe VI on an evening visit to the Ruber International Clinic in Madrid.
Queen Letizia of Spain looked typically stylish on Thursday as she attended the National Innovation and Design Awards in Las Palmas, Gran Canaria, with her husband King Felipe.
King Felipe's mother, Queen Sofia, was admitted to the Ruber Clinic in Madrid with a urinary tract infection on Tuesday
Queen Letizia has appointed María Dolores Ocaña Madrid as her new Queen's Secretariat.
Find out how the likes of the Spanish, Swedish and Danish royal families marked the Easter holidays