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PLOS ONE editors choose their favorite papers of the last 15 years.

Dengue virus infection is prevalent in tropical and sub-tropical regions of the world, which is fatal if untreated symptomatically. Emergence of new genotype within serotypes led to enhanced severity. The objective of the study is to identify the molecular characteristics of the DENV circulated during 2017 outbreak in Tamil Nadu, India and, to investigate the role of inflammatory cytokines in different ‘serotypes’ and in ‘dengue severity’. A total of 135 suspected samples were tested for DENV infection using IgM, IgG and qPCR assay; where 76 samples were positive for DENV and analysed ...

Profesor e Investigador Científico en Neurociencias, Universidad Complutense de Madrid Madrid, 28 de junio (The Conversation).- A finales de 2019 se confirmaron los primeros casos de infección por SARS-CoV-2. Tal y como su nombre indica (SARS viene del inglés Severe Acute Respiratory Syndrome), se trata de un virus que afecta al tracto respiratorio produciendo síntomas característicos como congestión nasal, dificultad para respirar. A medida que la pandemia avanzaba, aumentó el número de pacientes con síntomas neurológicos leves como dolores de cabeza, o pérdida de olfato o a...

Press release content from Globe Newswire. The AP news staff was not involved in its creation. iTeos Therapeutics Announces New Preliminary Data Indicating Clinical Activity with its ... iTeos Therapeutics Inc.April 10, 2021 GMT Initial data from the Phase 1 dose escalation part of the Phase 1/2a trial in adult patients with advanced solid tumors indicated EOS-448 was generally well tolerated with no dose-limiting toxicities observed EOS-448 showed preliminary signs of clinical activity as a monotherapy, including a partial response in one pembrolizumab-resistant melanoma patient, and stable ...