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Vorasidenib Improves PFS in Grade 2 Gliomas With Manageable Safety Profile

Neither of the 2 current standards of care offers patients a cure. ....

United States , New York , Ingok Mellinghoff , World Health Organization , Department Of Neurology , Oncology At Memorial Sloan Kettering Cancer Center , American Society Of Clinical Oncology Annual Meeting , Clinical Oncology Annual , Evnin Family Chair , Memorial Sloan Kettering Cancer Center ,

ASCO: Vorasidenib Improves Progression-Free Survival in Grade 2 IDH-Mutant Glioma

Vorasidenib significantly improves progression-free survival among patients with grade 2 isocitrate dehydrogenase (IDH)-mutant glioma. ....

New York , United States , Memorial Sloan Kettering Cancer Center , Ingok Mellinghoff , American Society Of Clinical Oncology , Healthday News , New England Journal , American Society , Clinical Oncology , New York City ,

Vorasidenib Significantly Improves PFS in Grade 2 Gliomas With Manageable Safety Profile

Current standard of care gives 2 poor options to patients, neither of which cure grade 2 gliomas. ....

United States , Ingok Mellinghoff , World Health Organization , Department Of Neurology , American Society Of Clinical Oncology , Oncology At Memorial Sloan Kettering Cancer Center , Evnin Family Chair , Memorial Sloan Kettering Cancer Center , American Society , Clinical Oncology ,

Servier Presents Transformational Data from Pivotal Phase 3 INDIGO Trial of Vorasidenib in Recurrent or Residual Grade 2 IDH-Mutant Diffuse Glioma

Vorasidenib demonstrated an unprecedented improvement in progression free survival with a median of 27.7 months in patients with residual or recurrent grade 2. ....

United States , Nathan Mellor , Ingok Mellinghoff , Susan Pandya , Ingo Mellinghoff , Prnewswire Servier , Brock Greene , Memorial Sloan Kettering Cancer Center , Servier Pharmaceuticals , European Union , Department Of Neurology , Servier Group , Us Food Drug Administration , Clinical Development , New England Journal , American Society , Clinical Oncology , Memorial Sloan Kettering Cancer , Vice President Clinical Development , Cancer Metabolism Global Development Oncology , Drug Administration , New Drug Application , Central Nervous System ,

Vorasidenib first 'game changer' in 20 years for patients with IDH -mutant grade 2 glioma

CHICAGO — Vorasidenib significantly improved PFS while delaying time to next intervention among certain patients with grade 2 isocitrate dehydrogenase 1- or 2-mutant glioma, according to data presented at ASCO Annual Meeting.The findings, published simultaneously in The New England Journal of Medicine, showed efficacy across all patient subgroups. ....

United States , Devin Mclaughlin , Bymatthew Shinkle , Daniel Orringer , Ingok Mellinghoff , Vorasidenib Servier , Ashleyl Sumrall , Debiopharm Group , Memorial Sloan Kettering Cancer Center , Black Diamond Therapeutics , Puma Biotechnology , Voyager Therapeutics , General Electric , Thenew England Journal ,