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Pig Organ Transplants into Humans Reveals Crucial Cellular Changes

Discover minute cellular alterations triggered by pig heart and kidney transplants in humans, revealing insights into xenotransplantation. ....

Jef Boeke , Langone Health , Broad Institute , Institute For System Genetics , Grossman School Of Medicine , Nature Medicine , Rejection Mechanisms , Pig Kidney Xenotransplantation The , System Genetics , Multiomics Analysis , Immune Response , Pig Heart Xenotransplantation ,

Single-cell analysis reveals insights into immune responses during xenotransplantation

Surgical teams at NYU Langone Health performed the world's first genetically modified pig kidney transplants into a human body in September and November 2021, and then transplanted two pig hearts in the summer of 2022. ....

Jef Boeke , Brendan Keating , Grossman School Of Medicine , Department Of Surgery , Institute For System Genetics , Nyu Langone Health , Langone Health , Broad Institute , Nature Medicine , System Genetics ,

Studies reveal cell-by-cell changes caused when pig hearts and kidneys are transplanted into humans

Surgical teams at NYU Langone Health performed the world s first genetically modified pig kidney transplant into a human body in September and November 2021, and then transplanted two pig hearts in the summer of 2022. These procedures were done in patients declared dead based on neurologic criteria (decedents) and maintained on ventilators with the consent of their families. Demonstrating the field s progress, NYU Langone in April 2024 transplanted a pig kidney into a living patient. ....

Jef Boeke , Brendan Keating , Eloi Schmauch , Langone Health , Institute For System Genetics , Department Of Surgery , Grossman School Of Medicine , Broad Institute , Nature Medicine , System Genetics ,

Studies Reveal Cell-By-Cell Changes Caused When Pig Hearts And Kidneys Are Transplanted Into Humans

NEW YORK, May 21, 2024 /PRNewswire/ Surgical teams at NYU Langone Health performed the world s first genetically modified pig kidney transpl ....

Southwest Finland , Saudi Arabia , France General , Vasishta Tatapudi , Elaina Weldon , Jiangshan Bai , Sophie Widawsky , David Andrijevic , Yinan Zhu , Philip Sommer , Mercy Williams , Ziyan Lin , Weimin Zhang , Brendan Keating , Wanqing Pan , Adam Griesemer , Nader Moazami , Robert Montgomery , Chenchen Zhu , Ian Jaffe , Maedeh Mohebnasab , Brian Piening , Adriana Heguy , Massimo Mangiola , Qian Guo , Simon Williams ,

Change in gene code may explain how human ancestors lost tails

Change in gene code may explain how human ancestors lost tails
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Bo Xia , Emily Huang , Guisheng Zhao , Aleksandra Wudzinska , Gwen Ellis , Alexander Miller , Matthew Maurano , Yu Zhao , Jefd Boeke , Weimin Zhang , Jeremy Dasen , Camila Coelho , Yinan Zhu , Hannah Ashe , Itai Yanai , Judith Bergstein , Yong Kim , Langone Health Rodent Genetic Engineering Laboratory , National Institutes Of Health , Harvard Society Of Fellows , Institute For System Genetics , Grossman School Of Medicine , Institute For Systems Genetics , Langone Health , Broad Institute , Harvard Society ,