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Efficacy and safety of aldosterone synthase inhibition with and without empagliflozin for chronic kidney disease: a randomised, controlled, phase 2 trial

Efficacy and safety of aldosterone synthase inhibition with and without empagliflozin for chronic kidney disease: a randomised, controlled, phase 2 trial
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United Kingdom , J Clin Hypertens , Clin Pharmacokinet , Nephrol Hypertens , Dial Transplant , Practice Guideline , Diabetes Management , Chronic Kidney Disease , Chronic Kidney Dis , Clin Hypertens , Hypertens Rep , Opin Nephrol Hypertens , Int Rep , Diabetes Endocrinol , Englj Med ,

Sodium bicarbonate for kidney transplant recipients with metabolic acidosis in Switzerland: a multicentre, randomised, single-blind, placebo-controlled, phase 3 trial

In adult kidney transplant recipients, correction of metabolic acidosis by treatment
with sodium bicarbonate over 2 years did not affect the decline in estimated GFR.
Thus, treatment with sodium bicarbonate should not be generally recommended to preserve
estimated GFR (a surrogate marker for graft function) in kidney transplant recipients
with chronic kidney disease who have metabolic acidosis. ....

United Kingdom , City Of , Semin Nephrol , Nephrol Hypertens , Clin Nephrol , National Institute For Health , Work Group , Kidney Blood Press Res , Summary Of The British Transplantation Society Guidelines , Dial Transplant , Blood Press Res , Int Rep , Preserve Transplant Study , Intern Med , Opin Nephrol Hypertens , Care Excellence , Practice Guideline , British Transplantation Society Guidelines , Improving Global Outcomes , Transplant Work ,