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West Side News & Notes - Akron.com

Fairlawn mayor to retire FAIRLAWN Fairlawn Mayor William Roth Jr. announced his retirement, with his last day in office being Nov. 30. Fairlawn City Council President Russell Sharnsky, 67, will become mayor upon Roth’s retirement and fill out the term. He will have to file to run in the 2023 November General Election to ....

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CIO 100 US: 8 award-winning healthcare IT projects

Healthcare organizations are increasingly embracing digital initiatives to expedite evaluations, better share medical records, and improve patient care. ....

United States , Miller School , University Of Miami , Suja Chandrasekaran , Chedmed Intunehealth , Michael Restuccia , Tytocare Io , Jeri Koester , Taylor Davis , Abhishek Singh , Michael Garcia , Onyeka Nchege , David Reis , Hernando Celada , Sunil Dadlani , Atlantic Health , Commonspirit Health , Novant Health , University Of Miami Health System , Drug Administration , Atlantic Health System , Chartis Group , N Atlantic Health System , Teledoc Health Robot , Everest Group , Marshfield Clinic Health System ,

Frontiers | A Polygenic Score for Type 2 Diabetes Improves Risk Stratification Beyond Current Clinical Screening Factors in an Ancestrally Diverse Sample

A substantial proportion of the adult US population with type 2 diabetes (T2D) are undiagnosed, calling into question the comprehensiveness of current screening practices, which primarily rely on age, family history, and body mass index (BMI). We hypothesized that a polygenic score (PGS) may serve as a complementary tool to identify high-risk individuals. The T2D PGS maintained predictive utility after adjusting for family history and combining genetics with family history led to even more improved disease risk prediction. We observed that the PGS was meaningfully related to age of onset with implications for screening practices: there was a linear and statistically significant relationship between the PGS and T2D onset (-1.3 years per standard deviation of the PGS). Evaluation of U.S. Preventive Task Force and a simplified version of American Diabetes Association screening guidelines showed that addition of a screening criterion for those above the 90th percentile of the PGS provided ....

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