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Evidence for a role of human blood-borne factors in mediating age-associated changes in molecular circadian rhythms

Evidence for a role of human blood-borne factors in mediating age-associated changes in molecular circadian rhythms
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Revealing lncRNA biomarkers related to COPD

Providing a landscape of ceRNA network, which helps to reveal the pathophysiological mechanisms of COPD and shed light on novel therapeutic strategies ....

Network Node Degree , Network Analysis , Gene Expression Omnibus , Differential Expression , Interacting Genes , Gene Ontology , Kyoto Encyclopedia , Screened Based , Network Node ,

IL8 & IL1β expression in bronchial epithelial cells in COPD

IL8 & IL1β expression in bronchial epithelial cells in COPD
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Modification regulators in abdominal aortic aneurysm

Modification regulators in abdominal aortic aneurysm
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[Full text] Sinomenine Inhibits the Growth of Ovarian Cancer Cells Through the Sup

CDK1,
BUB1) play important roles in the progression of G2/M phase in the cell cycle.
30,31 Furthermore, real-time PCR analysis was used to verify the results of transcriptome sequencing and the results indicated that the expression trends of the top 18 ranked degree genes were consistent with those obtained by RNA-seq, suggesting that the RNA-seq data reliably reflected the gene expression alterations (Figure 4B). According to the RNA-seq and real-time PCR results, the expressions of cell cycle regulated genes, such as
CDK1,
PLK1, and
BUB1, were significantly decreased after sinomenine treatment. These results were also in accord with the cell phenotype experiments. ....

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