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IFM will be eligible for potential milestone payments in aggregate value of up to $835 million, giving Novartis full rights to its STING antagonist program
<p>For his work in furthering the understanding of how the human immune system senses dangerous invading pathogens, Bingxu Li has received the 2024 Michelson Philanthropies & <em>Science</em> Prize for Immunology. Li’s prize-winning essay investigates the role that Stimulator of Interferon Genes, or STING, plays in including multiple distinct defenses against viruses, bacteria, and tumors and in orchestrating myriad downstream responses upon activation – resolving a significant mystery in the field of innate immunity. The sensing ...
A key element in the aging process is characterized by mild inflammation, which contributes to the decline and impairment associated with aging.
Researchers have unveiled the key role of the cGAS/STING molecular signaling pathway in driving chronic inflammation and functional decline during aging.
Researchers at Monash University report they have discovered a key mechanism in the body’s immune system that helps control the inflammatory response to infection.