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Filgotinib Reduces Flare Risk in Uveitis in Phase 2 Study

Phase 2 data on filgotinib show a reduction in risk of flare in patients with uveitis and good tolerance in one of the first studies of a JAK inhibitor in uveitis. ....

United Kingdom , Robin Besuyen , Filgotinib Jyseleca , Xenofon Baraliakos , Gilead Sciences , European Union , Drug Administration , Ruhr University Bochum Germany , International Congress On Spondyloarthritides , International Congress , Ruhr University Bochum , Double Blind Trial , Very Few , Treatment Failure Favored Filgotinib , Intraocular Inflammation , Rheumatoid Arthritis , Posterior Uveitis , Esnier Boeck Disease , Ulcerative Colitis , Anti Tnf , Anti Tumor Necrosis Factor , Biologic Therapy , Vision Care And Maintenance , Social Issues , Visual Acuity ,

ASDAS Measurement of SpA Activity Not Influenced by Gender

Researchers studied how gender affects the reporting of patient outcomes across commonly used scoring methods and indices in the spectrum of spondyloarthritis subtypes in a multinational study. ....

Martin Rudwaleit , Diego Benavent , Health Index , Paz University Hospital , International Congress On Spondyloarthritides , Assessment Of Spondyloarthritis International Society , Ankylosing Spondylitis Disease Activity Score , International Congress , Klinikum Bielefeld , Study Across Spa Phenotypes , Disease Scoring Methods , Spondyloarthritis International Society , Bath Ankylosing Spondylitis Functional Index , European Quality , Life Five Dimensions , Psoriatic Arthritis , Ankylosing Spondylitis Bechterews Disease , Social Issues , Ankylosing Spondylitis , Sex Gender Difference , Back Pain , Pain Management , Pain Management , C Reactive Protein , Inflammatory Bowel Disease , Nflammatory Bowel Disease Ibd ,

Limited Role for COX-2, TNFi in Reducing AxSpA Progression

There was a strong, but not statistically significant, signal of reduced spinal structural damage with the combination of a selective COX-2 inhibitor and a TNF inhibitor in axial spondyloarthritis. ....

Walterp Maksymowych , University Of Alberta , University Medicine , International Congress On Spondyloarthritides , Fabian Proft , International Congress , Stoke Ankylosing Spondylitis Spinal Score , Statistical Significance , Numerical Difference , Ankylosing Spondylitis Disease Activity Score , Ankylosing Spondylitis , Acute Pain , Ankylosing Spondylitis Bechterews Disease , Cox 2 Inhibitor , Yclooxygenase 2 Inhibitor , Pain Management , Pain Management , Nonsteroidal Anti Inflammatory Drugs Nsaids , Nonsteroidal Anti Inflammatory Drugs , Rug Nonsteroidal Anti Inflammatory , Anti Inflammatory Agents , Disease Modifying Antirheumatic Drugs Dmards , Mard Disease Modifying Antirheum ,

Bimekizumab Effective for AxSpA Regardless of Prior TNFi Use

Data after 24 weeks of treatment with bimekizumab in patients with axial spondyloarthritis show good responses overall regardless of prior experience with a tumor necrosis factor inhibitor. ....

Xenofon Baraliakos , Eli Lilly , Bristol Myers Squibb , European Alliance Of Associations , Assessment In Spondyloarthritis International Society , European Union , Ruhr University Bochum Germany , International Congress On Spondyloarthritides , International Congress , Ruhr University Bochum , European Alliance , Spondyloarthritis International Society , Fabian Proft , Medical University , None Drug , Ankylosing Spondylitis Disease Activity Score , Bath Ankylosing Spondylitis Functional Index , Response Seen Regardless , Merck Sharp , Pain Management , Pain Management , Ankylosing Spondylitis Bechterews Disease , Ankylosing Spondylitis , Biologic Therapy , Social Issues , Fungal Infection ,

Differentiating Axial Disease in PsA Versus AS With Psoriasis

Some identifiers of patients with isolated axial psoriatic arthritis were older age at diagnosis, psoriatic nail lesions, and absence of inflammatory back pain. ....

Noord Holland , Dafnad Gladman , Robert Landew , University Of Toronto , Amsterdam University Medical Center , Group For Research , International Congress On Spondyloarthritides , Fabian Proft , International Congress , Axial Involvement , Psoriatic Arthritis , Clinical Management , Patient Care Management , Ankylosing Spondylitis Bechterews Disease , Back Pain , Pain Management , Pain Management , Ankylosing Spondylitis , Clinical Research , Clinical Trials , Linical Studies ,