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FDA Grants Orphan Drug Designation to LYT-200 in AML

The FDA has granted orphan drug designation to LYT-200 for the treatment of acute myeloid leukemia. ....

United States , Amir Fathi , Aleksandra Filipovic , Leukemia Program At Massachusetts , Puretech Health , Oncology Congress , International Prognostic Scoring System , Leukemia Program , Massachusetts General Hospital ,

Gene Mutations Linked to Adverse Outcomes in AML/MDS

A rare mutation on the BCL6-corepressor gene correlated with worse overall survival in patients with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). However, allogenic stem cell transplant improved survival in this population.
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World Health Organization , International Prognostic Scoring System , Auer Rods ,

Study Describes Characteristics, Outcomes of Patients With Low-Risk MDS

Investigators say a better understanding of risk factors and categories can help personalize care for patients living with myelodysplastic syndrome (MDS). ....

Moffitt Cancer Center , International Prognostic Scoring System , Image Credit , Myelodysplastic Syndromes , Lr Mds , Moffitt Cancer Center , High Risk Mds , Low Risk Mds ,

Luspatercept Receives Positive EU CHMP Opinion for Treatment of Anemia in Lower-Risk MDS

Luspatercept has been recommended for approval by the EMA for patients with transfusion-dependent anemia and lower-risk myelodysplastic syndromes. ....

United States , Bristol Myers Squibb Reblozyl , Anne Kerber , World Health Organization , European Commission , European Union , Bristol Myers Squibb , Head Of Late Clinical Development , International Prognostic Scoring System , European Medicines Agency , Medicinal Products , Human Use , Late Clinical Development , Cell Therapy , Revised International Prognostic Scoring System , Myers Squibb , Myelodysplastic Syndromes , Della Porta , Myeloproliferative Neoplasms ,

Updates to MDS Classification Complicate Yet Better Inform Treatment Navigation in MDS

Mikkael A. Sekeres, MD, MS, discusses the influence of therapeutic developments and conflicting classification systems on the management of MDS. ....

United States , University Of Miami , Namrata Chandhok , Mikkaela Sekeres , World Health Organization , Division Of Hematology , International Prognostic Scoring System , Sylvester Comprehensive Cancer Center , University Of Miami Health System , International Consensus Classification , Onclive State , Science Summit , Leukemia Section , Miami Health System , Mds Classification Systems , Risk Stratification , Classification Of Myelodysplastic Syndromes , International Prognostic Scoring System , Updates To Mds Classification ,