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Greater disease activity was not evident in MS patients given a next Ocrevus infusion at times beyond the recommended every six months.
Compared to an extended or long interval, ten weeks apart, which as you know many people in the uk have had and we found two main thing is, firstly antibody levels fell significantly during the ten week long interval after the first dose. but t cell responses were maintained. and on average, people who had the long interval dosing ended up with higher antibody responses after the second dose compared to those with the short interval, including variants of concern. it's important to say that these are at a population level not individual, and there's a lot of variability in immune response and ...
Across five centres in england and compared how two different arms of immune response, antibodies and t cells, responded in people given the pfizer vaccine according to a short course, so average three weeks apart compared to an extended or long interval, ten weeks apart, which as you know many people in the uk have had and we found two main thing is, firstly antibody levels fell significantly during the ten week long interval after the first dose. but t cell responses were maintained. and on average, people who had the long interval dosing ended up with higher antibody responses after the sec...