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"Intussusception and COVID-19 in Children: A Systematic Review and Meta" by Saad Alhumaid, Zainab Al Alawi et al.

Background: Intussusception (ISN) post-COVID-19 infection in children is rare but can occur. SARS-CoV-2 may play a role in the pathogenesis of ISN and trigger immune activation and mesenteric adenitis, which predispose peristaltic activity to “telescope” a proximal bowel segment into the distal bowel lumen. Objectives: To estimate the prevalence of SARS-CoV-2 infection in ISN children and analyze the demographic parameters, clinical characteristics and treatment outcomes in ISN pediatric patients with COVID-19 illness. Methods: We performed this systematic review following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Studies reporting on the incidence of ISN post-SARS-CoV-2 infection in children, published from 1 December 2019 until 1 October 2022, in PROQUEST, MEDLINE, EMBASE, PUBMED, CINAHL, WILEY ONLINE LIBRARY, SCOPUS and NATURE, with a restriction to articles available in the English language, were included. Results: Of the 169 papers that w ....

Preferred Reporting Items , Systematic Reviews , Covid 19 , Meta Analysis , Ars Cov 2 , Systematic Review ,

Research suggests that antiviral defense regulates intestinal function and overall gut health

Besides the skin, the digestive tract is the tissue that is most exposed to environmental influences such as bacteria and viruses ....

Franziska Ottens , Sotirios Efstathiou , Thorsten Hoppe , Professor Dr Thorsten Hoppe , Nature Cell , Ews India ,

Study explores how common immune cells might prevent intestinal healing

Karolinska Institutet researchers have demonstrated that B lymphocytes, on which the efficient operation of the immune system depends, can occasionally cause more harm than good since their numbers sharply increase following intestinal trauma, impeding the healing process. ....

Karolinska Institutet , Gustavo Monasterio , Eduardo Villablanca , Department Of Medicine Solna , Ews India ,