Research traces molecular link from gene to late-onset retinal degeneration
Scientists have discovered that gene therapy and the diabetes drug metformin may be potential treatments for late-onset retinal degeneration (L-ORD
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Scientists have discovered that gene therapy and the diabetes drug metformin may be potential treatments for late-onset retinal degeneration (L-ORD
A genome-wide association study (GWAS) on 120 primary studies including 1.65 million participants including nearly 350,000 participants from non-European ancestries, shows including participants of diverse ancestries facilitates the identification of genomic variants that are more strongly associated with cardiovascular diseases. The authors noted, trans-ancestry GWAS will help identify effector genes and allow for accelerated biological insight and identification of potential drug targets.
In a large-scale study of people from diverse ancestries, researchers narrowed down the number of genomic variants that are strongly associated with blood lipid levels and generated a polygenic risk score to predict elevated low-density lipoprotein cholesterol levels, a major risk factor for heart disease.
In a large-scale study of people from diverse ancestries, researchers narrowed down the number of genomic variants that are strongly associated with blood lipid levels and generated a polygenic risk score to predict elevated low-density lipoprotein cholesterol levels, a major risk factor for heart disease.
The American Society for Hematology 2021 Annual Meeting will be a hybrid affair packed with great science, say the meeting organizers.