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 E-Mail IMAGE: Super-resolution microscopy of a neuron shows the accumulation of lipids within lysosomes that occurs when the gene for prosaposin is suppressed. view more  Credit: UCSF When a single gene in a cell is turned on or off, its resulting presence or absence can affect the function and survival of the cell. In a new study appearing May 24 in Nature Neuroscience, UCSF researchers have successfully catalogued this effect in the human neuron by separately toggling each of the 20,000 genes in the human genome. In doing so, they've created a technique that can be employed for...

Dr. Andrew Singleton Dr. Andrew B. Singleton is the director of a new NIH intramural research effort, the Center for Alzheimer’s and Related Dementias (CARD). He has been serving as CARD acting director since its construction plan launch in January 2020. He is set to stimulate and lead collaborative research group projects to expand knowledge of the biological mechanisms of Alzheimer’s and related dementias, and to explore methods of treatment and prevention.  “With his decades of experience leading cutting-edge neurodegenerative disease research, Andy is uniquely qualified to inspire ...

Claudia Philipp/Wuppertal Zoo Germany Mhudiblu, a female bonobo whose genome was sequenced, holds her baby daughter Akeema Chimpanzees and bonobos...

The GBMAD Section’s mission is to discover genes that contribute to the risk for mood and anxiety disorders.

Francesca Belouad, MA, is a Research Psychologist in GEB-SDGE. She is responsible for administrating interviews and overseeing clinical aspects of the NIMH Family Study. Francesca has been employed as a Research Psychologist at the NIMH since 2000, when she was recruited by Dennis Charney, MD, during the formation of the Mood and Anxiety Disorders Research Program. Prior to this, she held research positions at the Section on Development Psychology at the NIMH, Outpatient Psychiatry at the Washington Veterans Medical Center, and the Department of Medical and Clinical Psychology at the Uniform...