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Pirtobrutinib Decreased the Emergence of BTK C481 Clones in Patients With CLL

Published: October 9, 2023

Findings from the phase 1/2 BRUIN trial of show a distinct genetic evolution in patients with B-cell malignancies. However, the baseline BTK mutations did not impede pirtobrutinib’s effectiveness.

Source: targetedonc.com

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United StatesInternational Workshop On Chronic Lymphocytic LeukemiaChronic Lymphocytic LeukemiaChronic Lymphocytic LeukemiaBruton Tyrosine Kinase Inhibitor2023 International Workshop On Chronic Lymphocytic Leukemia Iwcll 2023