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Extending the Frontiers of Checkpoint Inhibition in Merkel Cell Carcinoma

In the treatment of unresectable or metastatic Merkel cell carcinoma, immune checkpoint inhibitors have activity and tolerability.

Boston , Massachusetts , United-states , Netherlands , Dana-farber-cancer-institute , Germany , American , Avelumab-bavencio , Jamesa-decaprio , Kangc-retifanlimab , American-society-of-clinical-oncology-annual-meeting , Harvard-medical-school

Kymera Therapeutics Presents Preclinical Data Demonstrating Activity of MDM2 Degraders in Acute Myeloid Leukemia and Merkel Cell Carcinoma

Preclinical models highlight the potential of KT-253 as a monotherapy and combined with the standard of care agent venetoclax for the treatment of Acute Myeloid Leukemia MDM2 degraders shown to...

Tokyo , Japan , Massachusetts , United-states , Watertown , Boston , Dana-farber-cancer-institute , Yogesh-chutake , Justine-koenigsberg , Varsha-ananthapadmanabhan , Jared-gollob , Todd-cooper

Kymera Therapeutics Presents Preclinical Data Demonstrating Activity of MDM2 Degraders in Acute Myeloid Leukemia and Merkel Cell Carcinoma - Kymera Therapeutics (NASDAQ:KYMR)

Kymera Therapeutics Presents Preclinical Data Demonstrating Activity of MDM2 Degraders in Acute Myeloid Leukemia and Merkel Cell Carcinoma - Kymera Therapeutics (NASDAQ:KYMR)
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Massachusetts , United-states , Boston , Japan , Dana-farber-cancer-institute , Tokyo , Watertown , Jamesa-decaprio , Varsha-ananthapadmanabhan , Yogesh-chutake , Jared-gollob , International-conference-on-molecular