They contradicted the traditional alternative that memory is maintained by neurons remaining persistently active, like an idling engine.While both the models allowed for information to be held in mind, only the versions that allowed for synapses to transiently change connections, or short-term synaptic plasticity, produced neural activity patterns that mimicked what was actually observed in real brains at work, the study said.The idea that brain cells maintain memories by being always on may be simpler, acknowledged senior author Earl K.